ELAC2-RABEP1 Fusion FISH Probe
The ELAC2-RABEP1 Fusion FISH Probe is used to confirm a fusion of the ELAC2 and RABEP1 genes. The fusion of the ELAC2 and RABEP1 genes has been associated with Cholangiocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELAC2-RABEP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-RERE | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-REOR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-REGO | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-REGR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-REAQ | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-ORRE | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-OROR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-ORGO | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GORE | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GOOR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GOGO | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GOGR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GRRE | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GROR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GRGO | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GRGR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-AQRE | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-AQOR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-AQGO | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-AQGR | 20 (40 μL) | 200 μL |
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| ELAC2-RABEP1-20-AQAQ | 20 (40 μL) | 200 μL |
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RABEP1 Gene Summary
The Rabaptin, RAB GTPase Binding Effector Protein 1 (RABEP1) gene is located on chr17 :5185557-5289132 at 17p13.2.
Gene Name: Rabaptin, RAB GTPase Binding Effector Protein 1
Chromosome: CHR17: 5185557 -5289132
Locus: 17p13.2
ELAC2 Gene Summary
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: ElaC Ribonuclease Z 2
Chromosome: CHR17: 12894928 -12921381
Locus: 17p12
Gene Diseases
The ELAC2 RABEP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cholangiocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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