EIF5B-LYG1 Fusion FISH Probe
The EIF5B-LYG1 Fusion FISH Probe is used to confirm a fusion of the EIF5B and LYG1 genes. The fusion of the EIF5B and LYG1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EIF5B-LYG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-RERE | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-REOR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-REGO | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-REGR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-REAQ | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-ORRE | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-OROR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-ORGO | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GORE | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GOOR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GOGO | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GOGR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GRRE | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GROR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GRGO | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GRGR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-AQRE | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-AQOR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-AQGO | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-AQGR | 20 (40 μL) | 200 μL |
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| EIF5B-LYG1-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF5B Gene Summary
Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008]
Gene Name: Eukaryotic Translation Initiation Factor 5B
Chromosome: CHR2: 99953833 -100016728
Locus: 2q11.2
LYG1 Gene Summary
The Lysozyme G1 (LYG1) gene is located on chr2 :99900700-99917639 at 2q11.2.
Gene Name: Lysozyme G1
Chromosome: CHR2: 99900700 -99917639
Locus: 2q11.2
Gene Diseases
The EIF5B LYG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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