EIF4G3-NSUN4 Fusion FISH Probe
The EIF4G3-NSUN4 Fusion FISH Probe is used to confirm a fusion of the EIF4G3 and NSUN4 genes. The fusion of the EIF4G3 and NSUN4 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EIF4G3-NSUN4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-RERE | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-REOR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-REGO | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-REGR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-REAQ | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-ORRE | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-OROR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-ORGO | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-ORAQ | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GORE | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GOOR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GOGO | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GOGR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GOAQ | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GRRE | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GROR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GRGO | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GRGR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-GRAQ | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-AQRE | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-AQOR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-AQGO | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-AQGR | 20 (40 μL) | 200 μL |
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| EIF4G3-NSUN4-20-AQAQ | 20 (40 μL) | 200 μL |
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EIF4G3 Gene Summary
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
Gene Name: Eukaryotic Translation Initiation Factor 4 Gamma 3
Chromosome: CHR1: 21132784 -21503381
Locus: 1p36.12
NSUN4 Gene Summary
The NOP2/Sun RNA Methyltransferase Family Member 4 (NSUN4) gene is located on chr1 :46806389-46830690 at 1p33.
Gene Name: NOP2/Sun RNA Methyltransferase Family Member 4
Chromosome: CHR1: 46806389 -46830690
Locus: 1p33
Gene Diseases
The EIF4G3 NSUN4 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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