EIF4G1-AEBP1 Fusion FISH Probe
The EIF4G1-AEBP1 Fusion FISH Probe is used to confirm a fusion of the EIF4G1 and AEBP1 genes. The fusion of the EIF4G1 and AEBP1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EIF4G1-AEBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-RERE | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-REOR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-REGO | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-REGR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-OROR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GORE | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GROR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| EIF4G1-AEBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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AEBP1 Gene Summary
This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]
Gene Name: AE Binding Protein 1
Chromosome: CHR7: 44143959 -44154159
Locus: 7p13
EIF4G1 Gene Summary
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
Gene Name: Eukaryotic Translation Initiation Factor 4 Gamma 1
Chromosome: CHR3: 184032282 -184053146
Locus: 3q27.1
Gene Diseases
The EIF4G1 AEBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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