EIF3K-PPP2R2A Fusion FISH Probe
The EIF3K-PPP2R2A Fusion FISH Probe is used to confirm a fusion of the EIF3K and PPP2R2A genes. The fusion of the EIF3K and PPP2R2A genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EIF3K-PPP2R2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-RERE | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-REOR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-REGO | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-REGR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-REAQ | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-ORRE | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-OROR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-ORGO | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GORE | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GOOR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GOGO | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GOGR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GRRE | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GROR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GRGO | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GRGR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-AQRE | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-AQOR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-AQGO | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-AQGR | 20 (40 μL) | 200 μL |
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| EIF3K-PPP2R2A-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R2A Gene Summary
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Gene Name: Protein Phosphatase 2 Regulatory Subunit Balpha
Chromosome: CHR8: 26149006 -26230195
Locus: 8p21.2
EIF3K Gene Summary
The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]
Gene Name: Eukaryotic Translation Initiation Factor 3 Subunit K
Chromosome: CHR19: 39109721 -39127595
Locus: 19q13.2
Gene Diseases
The EIF3K PPP2R2A Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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