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EIF2C3-PIK3CD Fusion FISH Probe

The EIF2C3-PIK3CD Fusion FISH Probe is used to confirm a fusion of the EIF2C3 and PIK3CD genes. The fusion of the EIF2C3 and PIK3CD genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EIF2C3-PIK3CD-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-RERE 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-REOR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-REGO 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-REGR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-REAQ 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-ORRE 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-OROR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-ORGO 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-ORAQ 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GORE 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GOOR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GOGO 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GOGR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GOAQ 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GRRE 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GROR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GRGO 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GRGR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-GRAQ 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-AQRE 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-AQOR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-AQGO 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-AQGR 20 (40 μL) 200 μL
EIF2C3-PIK3CD-20-AQAQ 20 (40 μL) 200 μL

PIK3CD Gene Summary

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]

Gene Name: Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Delta

Chromosome: CHR1: 9711789 -9789172

Locus: 1p36.22

Gene Diseases

The EIF2C3 PIK3CD Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

High-throughput Sequencing of Subcutaneous Panniculitis-like T-Cell Lymphoma Reveals Candidate Pathogenic Mutations

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cancer that’s challenging to distinguish from lupus panniculitis (LP). Few studies have been conducted on the genetic and molecular development of the disease. This team performed whole-exome sequencing on 4 SPTCLs and 1 systemic T-cell lymphoma, along with 2 cases of LP. They also used targeted sequencing to analyze 41 genes (with known implications across hematolyhpoid malignancies) on 5 additional SPTCL biopsies. Empire Genomics’ PDCD1 and PIK3CD FISH probes were used to detect copy number variants in the 2 genes, which are abnormalities associated with lymphoma but not LP.