EIF2AK4-AVEN Fusion FISH Probe
The EIF2AK4-AVEN Fusion FISH Probe is used to confirm a fusion of the EIF2AK4 and AVEN genes. The fusion of the EIF2AK4 and AVEN genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EIF2AK4-AVEN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-RERE | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-REOR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-REGO | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-REGR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-REAQ | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-ORRE | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-OROR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-ORGO | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-ORAQ | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GORE | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GOOR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GOGO | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GOGR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GOAQ | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GRRE | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GROR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GRGO | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GRGR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-GRAQ | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-AQRE | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-AQOR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-AQGO | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-AQGR | 20 (40 μL) | 200 μL |
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| EIF2AK4-AVEN-20-AQAQ | 20 (40 μL) | 200 μL |
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AVEN Gene Summary
The Apoptosis And Caspase Activation Inhibitor (AVEN) gene is located on chr15 :34158427-34331303 at 15q14.
Gene Name: Apoptosis And Caspase Activation Inhibitor
Chromosome: CHR15: 34158427 -34331303
Locus: 15q14
EIF2AK4 Gene Summary
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4
Chromosome: CHR15: 40226346 -40327797
Locus: 15q15.1
Gene Diseases
The EIF2AK4 AVEN Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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