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EIF2AK4-AVEN Fusion FISH Probe

The EIF2AK4-AVEN Fusion FISH Probe is used to confirm a fusion of the EIF2AK4 and AVEN genes. The fusion of the EIF2AK4 and AVEN genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EIF2AK4-AVEN-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-RERE 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-REOR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-REGO 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-REGR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-REAQ 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-ORRE 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-OROR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-ORGO 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-ORAQ 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GORE 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GOOR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GOGO 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GOGR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GOAQ 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GRRE 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GROR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GRGO 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GRGR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-GRAQ 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-AQRE 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-AQOR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-AQGO 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-AQGR 20 (40 μL) 200 μL
EIF2AK4-AVEN-20-AQAQ 20 (40 μL) 200 μL

AVEN Gene Summary

The Apoptosis And Caspase Activation Inhibitor (AVEN) gene is located on chr15 :34158427-34331303 at 15q14.

Gene Name: Apoptosis And Caspase Activation Inhibitor

Chromosome: CHR15: 34158427 -34331303

Locus: 15q14

EIF2AK4 Gene Summary

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]

Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4

Chromosome: CHR15: 40226346 -40327797

Locus: 15q15.1

Gene Diseases

The EIF2AK4 AVEN Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.