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EHMT1-GRIN1 Fusion FISH Probe

The EHMT1-GRIN1 Fusion FISH Probe is used to confirm a fusion of the EHMT1 and GRIN1 genes. The fusion of the EHMT1 and GRIN1 genes has been associated with Breast Invasive Carcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EHMT1-GRIN1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EHMT1-GRIN1-20-RERE 20 (40 μL) 200 μL
EHMT1-GRIN1-20-REOR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-REGO 20 (40 μL) 200 μL
EHMT1-GRIN1-20-REGR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-REAQ 20 (40 μL) 200 μL
EHMT1-GRIN1-20-ORRE 20 (40 μL) 200 μL
EHMT1-GRIN1-20-OROR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-ORGO 20 (40 μL) 200 μL
EHMT1-GRIN1-20-ORAQ 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GORE 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GOOR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GOGO 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GOGR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GOAQ 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GRRE 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GROR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GRGO 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GRGR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-GRAQ 20 (40 μL) 200 μL
EHMT1-GRIN1-20-AQRE 20 (40 μL) 200 μL
EHMT1-GRIN1-20-AQOR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-AQGO 20 (40 μL) 200 μL
EHMT1-GRIN1-20-AQGR 20 (40 μL) 200 μL
EHMT1-GRIN1-20-AQAQ 20 (40 μL) 200 μL

GRIN1 Gene Summary

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Gene Name: Glutamate Ionotropic Receptor NMDA Type Subunit 1

Chromosome: CHR9: 140033608 -140063214

Locus: 9q34.3

EHMT1 Gene Summary

The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

Gene Name: Euchromatic Histone Lysine Methyltransferase 1

Chromosome: CHR9: 140513443 -140730578

Locus: 9q34.3

Gene Diseases

The EHMT1 GRIN1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.