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EGFR-GNS Fusion FISH Probe

The EGFR-GNS Fusion FISH Probe is used to confirm a fusion of the EGFR and GNS genes. The fusion of the EGFR and GNS genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
EGFR-GNS-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
EGFR-GNS-20-RERE 20 (40 μL) 200 μL
EGFR-GNS-20-REOR 20 (40 μL) 200 μL
EGFR-GNS-20-REGO 20 (40 μL) 200 μL
EGFR-GNS-20-REGR 20 (40 μL) 200 μL
EGFR-GNS-20-REAQ 20 (40 μL) 200 μL
EGFR-GNS-20-ORRE 20 (40 μL) 200 μL
EGFR-GNS-20-OROR 20 (40 μL) 200 μL
EGFR-GNS-20-ORGO 20 (40 μL) 200 μL
EGFR-GNS-20-ORAQ 20 (40 μL) 200 μL
EGFR-GNS-20-GORE 20 (40 μL) 200 μL
EGFR-GNS-20-GOOR 20 (40 μL) 200 μL
EGFR-GNS-20-GOGO 20 (40 μL) 200 μL
EGFR-GNS-20-GOGR 20 (40 μL) 200 μL
EGFR-GNS-20-GOAQ 20 (40 μL) 200 μL
EGFR-GNS-20-GRRE 20 (40 μL) 200 μL
EGFR-GNS-20-GROR 20 (40 μL) 200 μL
EGFR-GNS-20-GRGO 20 (40 μL) 200 μL
EGFR-GNS-20-GRGR 20 (40 μL) 200 μL
EGFR-GNS-20-GRAQ 20 (40 μL) 200 μL
EGFR-GNS-20-AQRE 20 (40 μL) 200 μL
EGFR-GNS-20-AQOR 20 (40 μL) 200 μL
EGFR-GNS-20-AQGO 20 (40 μL) 200 μL
EGFR-GNS-20-AQGR 20 (40 μL) 200 μL
EGFR-GNS-20-AQAQ 20 (40 μL) 200 μL

EGFR Gene Summary

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Gene Name: Epidermal Growth Factor Receptor

Chromosome: CHR7: 55086724 -55275031

Locus: 7p11.2

GNS Gene Summary

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq, Jul 2008]

Gene Name: Glucosamine (N-acetyl)-6-sulfatase

Chromosome: CHR12: 65107221 -65153226

Locus: 12q14.3

Gene Diseases

The EGFR GNS Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.