EGFR-ERP44 Fusion FISH Probe
The EGFR-ERP44 Fusion FISH Probe is used to confirm a fusion of the EGFR and ERP44 genes. The fusion of the EGFR and ERP44 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EGFR-ERP44-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-RERE | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-REOR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-REGO | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-REGR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-REAQ | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-ORRE | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-OROR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-ORGO | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-ORAQ | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GORE | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GOOR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GOGO | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GOGR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GOAQ | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GRRE | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GROR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GRGO | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GRGR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-GRAQ | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-AQRE | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-AQOR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-AQGO | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-AQGR | 20 (40 μL) | 200 μL |
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| EGFR-ERP44-20-AQAQ | 20 (40 μL) | 200 μL |
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EGFR Gene Summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Gene Name: Epidermal Growth Factor Receptor
Chromosome: CHR7: 55086724 -55275031
Locus: 7p11.2
ERP44 Gene Summary
This gene encodes a member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. It has an inferred N-terminal signal peptide, a catalytically active thioredoxin (TRX) domain, two TRX-like domains and a C-terminal ER-retention sequence. This protein functions as a pH-regulated chaperone of the secretory pathway and likely plays a role in protein quality control at the endoplasmic reticulum - Golgi interface. [provided by RefSeq, Dec 2016]
Gene Name: Endoplasmic Reticulum Protein 44
Chromosome: CHR9: 102741462 -102861330
Locus: 9q31.1
Gene Diseases
The EGFR ERP44 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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