EGFR-DYM Fusion FISH Probe
The EGFR-DYM Fusion FISH Probe is used to confirm a fusion of the EGFR and DYM genes. The fusion of the EGFR and DYM genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EGFR-DYM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-RERE | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-REOR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-REGO | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-REGR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-REAQ | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-ORRE | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-OROR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-ORGO | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-ORAQ | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GORE | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GOOR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GOGO | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GOGR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GOAQ | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GRRE | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GROR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GRGO | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GRGR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-GRAQ | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-AQRE | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-AQOR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-AQGO | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-AQGR | 20 (40 μL) | 200 μL |
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| EGFR-DYM-20-AQAQ | 20 (40 μL) | 200 μL |
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EGFR Gene Summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Gene Name: Epidermal Growth Factor Receptor
Chromosome: CHR7: 55086724 -55275031
Locus: 7p11.2
DYM Gene Summary
This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]
Gene Name: Dymeclin
Chromosome: CHR18: 46570171 -46987079
Locus: 18q21.1
Gene Diseases
The EGFR DYM Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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