EGFR-ACADM Fusion FISH Probe
The EGFR-ACADM Fusion FISH Probe is used to confirm a fusion of the EGFR and ACADM genes. The fusion of the EGFR and ACADM genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EGFR-ACADM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-RERE | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-REOR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-REGO | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-REGR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-REAQ | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-ORRE | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-OROR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-ORGO | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-ORAQ | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GORE | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GOOR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GOGO | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GOGR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GOAQ | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GRRE | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GROR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GRGO | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GRGR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-GRAQ | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-AQRE | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-AQOR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-AQGO | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-AQGR | 20 (40 μL) | 200 μL |
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| EGFR-ACADM-20-AQAQ | 20 (40 μL) | 200 μL |
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ACADM Gene Summary
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Acyl-CoA Dehydrogenase Medium Chain
Chromosome: CHR1: 76190042 -76229355
Locus: 1p31.1
EGFR Gene Summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Gene Name: Epidermal Growth Factor Receptor
Chromosome: CHR7: 55086724 -55275031
Locus: 7p11.2
Gene Diseases
The EGFR ACADM Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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