EEF2-SEC63 Fusion FISH Probe
The EEF2-SEC63 Fusion FISH Probe is used to confirm a fusion of the EEF2 and SEC63 genes. The fusion of the EEF2 and SEC63 genes has been associated with Adrenocortical Carcinoma, and Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EEF2-SEC63-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-RERE | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-REOR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-REGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-REGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-OROR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GORE | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GROR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-SEC63-20-AQAQ | 20 (40 μL) | 200 μL |
|
EEF2 Gene Summary
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]
Gene Name: Eukaryotic Translation Elongation Factor 2
Chromosome: CHR19: 3976053 -3985461
Locus: 19p13.3
SEC63 Gene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Gene Name: SEC63 Homolog, Protein Translocation Regulator
Chromosome: CHR6: 108188959 -108279482
Locus: 6q21
Gene Diseases
The EEF2 SEC63 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Adrenocortical Carcinoma |
| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|