EEF2-PABPC1 Fusion FISH Probe
The EEF2-PABPC1 Fusion FISH Probe is used to confirm a fusion of the EEF2 and PABPC1 genes. The fusion of the EEF2 and PABPC1 genes has been associated with Uveal Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EEF2-PABPC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| EEF2-PABPC1-20-AQAQ | 20 (40 μL) | 200 μL |
|
EEF2 Gene Summary
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]
Gene Name: Eukaryotic Translation Elongation Factor 2
Chromosome: CHR19: 3976053 -3985461
Locus: 19p13.3
PABPC1 Gene Summary
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]
Gene Name: Poly(A) Binding Protein Cytoplasmic 1
Chromosome: CHR8: 101715143 -101734315
Locus: 8q22.3
Gene Diseases
The EEF2 PABPC1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uveal Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|