EEF2-DDX21 Fusion FISH Probe
The EEF2-DDX21 Fusion FISH Probe is used to confirm a fusion of the EEF2 and DDX21 genes. The fusion of the EEF2 and DDX21 genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EEF2-DDX21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-RERE | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-REOR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-REGO | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-REGR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-REAQ | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-ORRE | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-OROR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-ORGO | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-ORAQ | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GORE | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GOOR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GOGO | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GOGR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GOAQ | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GRRE | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GROR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GRGO | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GRGR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-GRAQ | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-AQRE | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-AQOR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-AQGO | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-AQGR | 20 (40 μL) | 200 μL |
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| EEF2-DDX21-20-AQAQ | 20 (40 μL) | 200 μL |
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EEF2 Gene Summary
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]
Gene Name: Eukaryotic Translation Elongation Factor 2
Chromosome: CHR19: 3976053 -3985461
Locus: 19p13.3
DDX21 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Gene Name: DExD-box Helicase 21
Chromosome: CHR10: 70715891 -70744279
Locus: 10q22.1
Gene Diseases
The EEF2 DDX21 Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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