EEF2-ARFGEF2 Fusion FISH Probe
The EEF2-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the EEF2 and ARFGEF2 genes. The fusion of the EEF2 and ARFGEF2 genes has been associated with Kidney Renal Papillary Cell Carcinoma, Thyroid Carcinoma, and Kidney Chromophobe. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EEF2-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| EEF2-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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EEF2 Gene Summary
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]
Gene Name: Eukaryotic Translation Elongation Factor 2
Chromosome: CHR19: 3976053 -3985461
Locus: 19p13.3
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The EEF2 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
| Thyroid Carcinoma |
| Kidney Chromophobe |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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