EEA1-CRADD Fusion FISH Probe
The EEA1-CRADD Fusion FISH Probe is used to confirm a fusion of the EEA1 and CRADD genes. The fusion of the EEA1 and CRADD genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EEA1-CRADD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-RERE | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-REOR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-REGO | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-REGR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-REAQ | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-ORRE | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-OROR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-ORGO | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-ORAQ | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GORE | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GOOR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GOGO | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GOGR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GOAQ | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GRRE | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GROR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GRGO | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GRGR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-GRAQ | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-AQRE | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-AQOR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-AQGO | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-AQGR | 20 (40 μL) | 200 μL |
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| EEA1-CRADD-20-AQAQ | 20 (40 μL) | 200 μL |
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EEA1 Gene Summary
The Early Endosome Antigen 1 (EEA1) gene is located on chr12 :93166284-93323107 at 12q22.
Gene Name: Early Endosome Antigen 1
Chromosome: CHR12: 93166284 -93323107
Locus: 12q22
CRADD Gene Summary
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: CASP2 And RIPK1 Domain Containing Adaptor With Death Domain
Chromosome: CHR12: 94071150 -94244531
Locus: 12q22
Gene Diseases
The EEA1 CRADD Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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