EDEM2-PEX14 Fusion FISH Probe
The EDEM2-PEX14 Fusion FISH Probe is used to confirm a fusion of the EDEM2 and PEX14 genes. The fusion of the EDEM2 and PEX14 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EDEM2-PEX14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-RERE | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-REOR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-REGO | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-REGR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-REAQ | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-ORRE | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-OROR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-ORGO | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-ORAQ | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GORE | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GOOR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GOGO | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GOGR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GOAQ | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GRRE | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GROR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GRGO | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GRGR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-GRAQ | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-AQRE | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-AQOR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-AQGO | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-AQGR | 20 (40 μL) | 200 μL |
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| EDEM2-PEX14-20-AQAQ | 20 (40 μL) | 200 μL |
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PEX14 Gene Summary
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Peroxisomal Biogenesis Factor 14
Chromosome: CHR1: 10535002 -10690815
Locus: 1p36.22
EDEM2 Gene Summary
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]
Gene Name: ER Degradation Enhancing Alpha-mannosidase Like Protein 2
Chromosome: CHR20: 33703159 -33735161
Locus: 20q11.22
Gene Diseases
The EDEM2 PEX14 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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