EDC3-SLC6A11 Fusion FISH Probe
The EDC3-SLC6A11 Fusion FISH Probe is used to confirm a fusion of the EDC3 and SLC6A11 genes. The fusion of the EDC3 and SLC6A11 genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EDC3-SLC6A11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-RERE | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-REOR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-REGO | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-REGR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-REAQ | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-ORRE | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-OROR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-ORGO | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-ORAQ | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GORE | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GOOR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GOGO | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GOGR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GOAQ | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GRRE | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GROR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GRGO | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GRGR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-GRAQ | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-AQRE | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-AQOR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-AQGO | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-AQGR | 20 (40 μL) | 200 μL |
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| EDC3-SLC6A11-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC6A11 Gene Summary
The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Name: Solute Carrier Family 6 Member 11
Chromosome: CHR3: 10857916 -10980146
Locus: 3p25.3
EDC3 Gene Summary
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]
Gene Name: Enhancer Of MRNA Decapping 3
Chromosome: CHR15: 74922898 -74988386
Locus: 15q24.1
Gene Diseases
The EDC3 SLC6A11 Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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