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E2F3-MYL4 Fusion FISH Probe

The E2F3-MYL4 Fusion FISH Probe is used to confirm a fusion of the E2F3 and MYL4 genes. The fusion of the E2F3 and MYL4 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
E2F3-MYL4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
E2F3-MYL4-20-RERE 20 (40 μL) 200 μL
E2F3-MYL4-20-REOR 20 (40 μL) 200 μL
E2F3-MYL4-20-REGO 20 (40 μL) 200 μL
E2F3-MYL4-20-REGR 20 (40 μL) 200 μL
E2F3-MYL4-20-REAQ 20 (40 μL) 200 μL
E2F3-MYL4-20-ORRE 20 (40 μL) 200 μL
E2F3-MYL4-20-OROR 20 (40 μL) 200 μL
E2F3-MYL4-20-ORGO 20 (40 μL) 200 μL
E2F3-MYL4-20-ORAQ 20 (40 μL) 200 μL
E2F3-MYL4-20-GORE 20 (40 μL) 200 μL
E2F3-MYL4-20-GOOR 20 (40 μL) 200 μL
E2F3-MYL4-20-GOGO 20 (40 μL) 200 μL
E2F3-MYL4-20-GOGR 20 (40 μL) 200 μL
E2F3-MYL4-20-GOAQ 20 (40 μL) 200 μL
E2F3-MYL4-20-GRRE 20 (40 μL) 200 μL
E2F3-MYL4-20-GROR 20 (40 μL) 200 μL
E2F3-MYL4-20-GRGO 20 (40 μL) 200 μL
E2F3-MYL4-20-GRGR 20 (40 μL) 200 μL
E2F3-MYL4-20-GRAQ 20 (40 μL) 200 μL
E2F3-MYL4-20-AQRE 20 (40 μL) 200 μL
E2F3-MYL4-20-AQOR 20 (40 μL) 200 μL
E2F3-MYL4-20-AQGO 20 (40 μL) 200 μL
E2F3-MYL4-20-AQGR 20 (40 μL) 200 μL
E2F3-MYL4-20-AQAQ 20 (40 μL) 200 μL

E2F3 Gene Summary

This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Gene Name: E2F Transcription Factor 3

Chromosome: CHR6: 20402136 -20493945

Locus: 6p22.3

MYL4 Gene Summary

Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Myosin Light Chain 4

Chromosome: CHR17: 45286427 -45301045

Locus: 17q21.32

Gene Diseases

The E2F3 MYL4 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.