DYNLT1-DUSP15 Fusion FISH Probe
The DYNLT1-DUSP15 Fusion FISH Probe is used to confirm a fusion of the DYNLT1 and DUSP15 genes. The fusion of the DYNLT1 and DUSP15 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DYNLT1-DUSP15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-RERE | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-REOR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-REGO | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-REGR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-REAQ | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-ORRE | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-OROR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-ORGO | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-ORAQ | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GORE | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GOOR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GOGO | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GOGR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GOAQ | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GRRE | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GROR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GRGO | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GRGR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-GRAQ | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-AQRE | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-AQOR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-AQGO | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-AQGR | 20 (40 μL) | 200 μL |
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| DYNLT1-DUSP15-20-AQAQ | 20 (40 μL) | 200 μL |
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DYNLT1 Gene Summary
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Gene Name: Dynein Light Chain Tctex-type 1
Chromosome: CHR6: 159057506 -159065804
Locus: 6q25.3
DUSP15 Gene Summary
The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Dual Specificity Phosphatase 15
Chromosome: CHR20: 30448869 -30458479
Locus: 20q11.21
Gene Diseases
The DYNLT1 DUSP15 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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