DYM-SLC14A2 Fusion FISH Probe
The DYM-SLC14A2 Fusion FISH Probe is used to confirm a fusion of the DYM and SLC14A2 genes. The fusion of the DYM and SLC14A2 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DYM-SLC14A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-RERE | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-REOR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-REGO | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-REGR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-REAQ | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-ORRE | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-OROR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-ORGO | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GORE | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GOOR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GOGO | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GOGR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GRRE | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GROR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GRGO | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GRGR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-AQRE | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-AQOR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-AQGO | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-AQGR | 20 (40 μL) | 200 μL |
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| DYM-SLC14A2-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC14A2 Gene Summary
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Solute Carrier Family 14 Member 2
Chromosome: CHR18: 42792946 -43263060
Locus: 18q12.3
DYM Gene Summary
This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]
Gene Name: Dymeclin
Chromosome: CHR18: 46570171 -46987079
Locus: 18q21.1
Gene Diseases
The DYM SLC14A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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