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DYM-OAS3 Fusion FISH Probe

The DYM-OAS3 Fusion FISH Probe is used to confirm a fusion of the DYM and OAS3 genes. The fusion of the DYM and OAS3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DYM-OAS3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DYM-OAS3-20-RERE 20 (40 μL) 200 μL
DYM-OAS3-20-REOR 20 (40 μL) 200 μL
DYM-OAS3-20-REGO 20 (40 μL) 200 μL
DYM-OAS3-20-REGR 20 (40 μL) 200 μL
DYM-OAS3-20-REAQ 20 (40 μL) 200 μL
DYM-OAS3-20-ORRE 20 (40 μL) 200 μL
DYM-OAS3-20-OROR 20 (40 μL) 200 μL
DYM-OAS3-20-ORGO 20 (40 μL) 200 μL
DYM-OAS3-20-ORAQ 20 (40 μL) 200 μL
DYM-OAS3-20-GORE 20 (40 μL) 200 μL
DYM-OAS3-20-GOOR 20 (40 μL) 200 μL
DYM-OAS3-20-GOGO 20 (40 μL) 200 μL
DYM-OAS3-20-GOGR 20 (40 μL) 200 μL
DYM-OAS3-20-GOAQ 20 (40 μL) 200 μL
DYM-OAS3-20-GRRE 20 (40 μL) 200 μL
DYM-OAS3-20-GROR 20 (40 μL) 200 μL
DYM-OAS3-20-GRGO 20 (40 μL) 200 μL
DYM-OAS3-20-GRGR 20 (40 μL) 200 μL
DYM-OAS3-20-GRAQ 20 (40 μL) 200 μL
DYM-OAS3-20-AQRE 20 (40 μL) 200 μL
DYM-OAS3-20-AQOR 20 (40 μL) 200 μL
DYM-OAS3-20-AQGO 20 (40 μL) 200 μL
DYM-OAS3-20-AQGR 20 (40 μL) 200 μL
DYM-OAS3-20-AQAQ 20 (40 μL) 200 μL

OAS3 Gene Summary

This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq, Jul 2008]

Gene Name: 2'-5'-oligoadenylate Synthetase 3

Chromosome: CHR12: 113376248 -113411054

Locus: 12q24.13

DYM Gene Summary

This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]

Gene Name: Dymeclin

Chromosome: CHR18: 46570171 -46987079

Locus: 18q21.1

Gene Diseases

The DYM OAS3 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.