DYM-MYO5B Fusion FISH Probe
The DYM-MYO5B Fusion FISH Probe is used to confirm a fusion of the DYM and MYO5B genes. The fusion of the DYM and MYO5B genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DYM-MYO5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-RERE | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-REOR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-REGO | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-REGR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-REAQ | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-ORRE | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-OROR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-ORGO | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-ORAQ | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GORE | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GOOR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GOGO | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GOGR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GOAQ | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GRRE | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GROR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GRGO | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GRGR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-GRAQ | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-AQRE | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-AQOR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-AQGO | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-AQGR | 20 (40 μL) | 200 μL |
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| DYM-MYO5B-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO5B Gene Summary
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009]
Gene Name: Myosin VB
Chromosome: CHR18: 47349155 -47721451
Locus: 18q21.1
DYM Gene Summary
This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]
Gene Name: Dymeclin
Chromosome: CHR18: 46570171 -46987079
Locus: 18q21.1
Gene Diseases
The DYM MYO5B Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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