DVL3-RFX6 Fusion FISH Probe
The DVL3-RFX6 Fusion FISH Probe is used to confirm a fusion of the DVL3 and RFX6 genes. The fusion of the DVL3 and RFX6 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DVL3-RFX6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-RERE | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-REOR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-REGO | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-REGR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-REAQ | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-ORRE | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-OROR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-ORGO | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-ORAQ | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GORE | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GOOR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GOGO | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GOGR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GOAQ | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GRRE | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GROR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GRGO | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GRGR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-GRAQ | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-AQRE | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-AQOR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-AQGO | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-AQGR | 20 (40 μL) | 200 μL |
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| DVL3-RFX6-20-AQAQ | 20 (40 μL) | 200 μL |
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DVL3 Gene Summary
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]
Gene Name: Dishevelled Segment Polarity Protein 3
Chromosome: CHR3: 183873283 -183891314
Locus: 3q27.1
RFX6 Gene Summary
The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.[provided by RefSeq, Sep 2010]
Gene Name: Regulatory Factor X6
Chromosome: CHR6: 117198375 -117253326
Locus: 6q22.1
Gene Diseases
The DVL3 RFX6 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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