DSTN-DTD1 Fusion FISH Probe
The DSTN-DTD1 Fusion FISH Probe is used to confirm a fusion of the DSTN and DTD1 genes. The fusion of the DSTN and DTD1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DSTN-DTD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-RERE | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-REOR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-REGO | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-REGR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-REAQ | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-ORRE | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-OROR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-ORGO | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GORE | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GOOR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GOGO | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GOGR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GRRE | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GROR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GRGO | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GRGR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-AQRE | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-AQOR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-AQGO | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-AQGR | 20 (40 μL) | 200 μL |
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| DSTN-DTD1-20-AQAQ | 20 (40 μL) | 200 μL |
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DSTN Gene Summary
The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Destrin, Actin Depolymerizing Factor
Chromosome: CHR20: 17550598 -17588652
Locus: 20p12.1
DTD1 Gene Summary
The protein encoded by this gene is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein binds the DNA unwinding element and plays a role in the initiation of DNA replication. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: D-tyrosyl-tRNA Deacylase 1
Chromosome: CHR20: 18568555 -18744560
Locus: 20p11.23
Gene Diseases
The DSTN DTD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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