DSTN-ARPC5 Fusion FISH Probe
The DSTN-ARPC5 Fusion FISH Probe is used to confirm a fusion of the DSTN and ARPC5 genes. The fusion of the DSTN and ARPC5 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DSTN-ARPC5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-RERE | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-REOR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-REGO | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-REGR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-REAQ | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-ORRE | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-OROR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-ORGO | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-ORAQ | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GORE | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GOOR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GOGO | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GOGR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GOAQ | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GRRE | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GROR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GRGO | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GRGR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-GRAQ | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-AQRE | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-AQOR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-AQGO | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-AQGR | 20 (40 μL) | 200 μL |
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| DSTN-ARPC5-20-AQAQ | 20 (40 μL) | 200 μL |
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ARPC5 Gene Summary
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Actin Related Protein 2/3 Complex Subunit 5
Chromosome: CHR1: 183595331 -183604985
Locus: 1q25.3
DSTN Gene Summary
The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Destrin, Actin Depolymerizing Factor
Chromosome: CHR20: 17550598 -17588652
Locus: 20p12.1
Gene Diseases
The DSTN ARPC5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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