DSP-RCAN2 Fusion FISH Probe
The DSP-RCAN2 Fusion FISH Probe is used to confirm a fusion of the DSP and RCAN2 genes. The fusion of the DSP and RCAN2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DSP-RCAN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-RERE | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-REOR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-REGO | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-REGR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-REAQ | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-ORRE | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-OROR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-ORGO | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GORE | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GOOR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GOGO | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GOGR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GRRE | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GROR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GRGO | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GRGR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-AQRE | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-AQOR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-AQGO | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-AQGR | 20 (40 μL) | 200 μL |
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| DSP-RCAN2-20-AQAQ | 20 (40 μL) | 200 μL |
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DSP Gene Summary
This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: Desmoplakin
Chromosome: CHR6: 7541869 -7586946
Locus: 6p24.3
RCAN2 Gene Summary
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Regulator Of Calcineurin 2
Chromosome: CHR6: 46188468 -46293531
Locus: 6p12.3
Gene Diseases
The DSP RCAN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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