DSE-PLEKHG1 Fusion FISH Probe
The DSE-PLEKHG1 Fusion FISH Probe is used to confirm a fusion of the DSE and PLEKHG1 genes. The fusion of the DSE and PLEKHG1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DSE-PLEKHG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-RERE | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-REOR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-REGO | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-REGR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-REAQ | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-ORRE | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-OROR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-ORGO | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GORE | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GOOR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GOGO | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GOGR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GRRE | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GROR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GRGO | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GRGR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-AQRE | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-AQOR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-AQGO | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-AQGR | 20 (40 μL) | 200 μL |
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| DSE-PLEKHG1-20-AQAQ | 20 (40 μL) | 200 μL |
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DSE Gene Summary
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016]
Gene Name: Dermatan Sulfate Epimerase
Chromosome: CHR6: 116601282 -116759442
Locus: 6q22.1
PLEKHG1 Gene Summary
The Pleckstrin Homology And RhoGEF Domain Containing G1 (PLEKHG1) gene is located on chr6 :150920998-151164799 at 6q25.1.
Gene Name: Pleckstrin Homology And RhoGEF Domain Containing G1
Chromosome: CHR6: 150920998 -151164799
Locus: 6q25.1
Gene Diseases
The DSE PLEKHG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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