DSCR3-MACROD2 Fusion FISH Probe
The DSCR3-MACROD2 Fusion FISH Probe is used to confirm a fusion of the DSCR3 and MACROD2 genes. The fusion of the DSCR3 and MACROD2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DSCR3-MACROD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-MACROD2-20-AQAQ | 20 (40 μL) | 200 μL |
|
DSCR3 Gene Summary
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]
Gene Name: DSCR3 Arrestin Fold Containing
Chromosome: CHR21: 38595725 -38639833
Locus: 21q22.13
MACROD2 Gene Summary
The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage. [provided by RefSeq, May 2017]
Gene Name: MACRO Domain Containing 2
Chromosome: CHR20: 13976145 -16033841
Locus: 20p12.1
Gene Diseases
The DSCR3 MACROD2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|