DSCR3-CTSH Fusion FISH Probe
The DSCR3-CTSH Fusion FISH Probe is used to confirm a fusion of the DSCR3 and CTSH genes. The fusion of the DSCR3 and CTSH genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DSCR3-CTSH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DSCR3-CTSH-20-AQAQ | 20 (40 μL) | 200 μL |
|
CTSH Gene Summary
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Gene Name: Cathepsin H
Chromosome: CHR15: 79214091 -79237420
Locus: 15q25.1
DSCR3 Gene Summary
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]
Gene Name: DSCR3 Arrestin Fold Containing
Chromosome: CHR21: 38595725 -38639833
Locus: 21q22.13
Gene Diseases
The DSCR3 CTSH Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|