DRAM1-SYCP3 Fusion FISH Probe
The DRAM1-SYCP3 Fusion FISH Probe is used to confirm a fusion of the DRAM1 and SYCP3 genes. The fusion of the DRAM1 and SYCP3 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DRAM1-SYCP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-RERE | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-REOR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-REGO | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-REGR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-REAQ | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-ORRE | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-OROR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-ORGO | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GORE | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GOOR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GOGO | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GOGR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GRRE | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GROR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GRGO | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GRGR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-AQRE | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-AQOR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-AQGO | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-AQGR | 20 (40 μL) | 200 μL |
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| DRAM1-SYCP3-20-AQAQ | 20 (40 μL) | 200 μL |
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SYCP3 Gene Summary
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010]
Gene Name: Synaptonemal Complex Protein 3
Chromosome: CHR12: 102122425 -102133250
Locus: 12q23.2
DRAM1 Gene Summary
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]
Gene Name: DNA Damage Regulated Autophagy Modulator 1
Chromosome: CHR12: 102271104 -102317401
Locus: 12q23.2
Gene Diseases
The DRAM1 SYCP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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