DRAM1-OVOL2 Fusion FISH Probe
The DRAM1-OVOL2 Fusion FISH Probe is used to confirm a fusion of the DRAM1 and OVOL2 genes. The fusion of the DRAM1 and OVOL2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DRAM1-OVOL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-RERE | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-REOR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-REGO | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-REGR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-REAQ | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-ORRE | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-OROR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-ORGO | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GORE | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GOOR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GOGO | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GOGR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GRRE | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GROR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GRGO | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GRGR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-AQRE | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-AQOR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-AQGO | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-AQGR | 20 (40 μL) | 200 μL |
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| DRAM1-OVOL2-20-AQAQ | 20 (40 μL) | 200 μL |
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DRAM1 Gene Summary
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]
Gene Name: DNA Damage Regulated Autophagy Modulator 1
Chromosome: CHR12: 102271104 -102317401
Locus: 12q23.2
OVOL2 Gene Summary
This gene encodes a member of the evolutionarily conserved ovo-like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N- and C-terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion, impaired vascularization, and heart anomalies. In humans, allelic variants of this gene have been associated with posterior polymorphous corneal dystrophy. [provided by RefSeq, Apr 2016]
Gene Name: Ovo Like Zinc Finger 2
Chromosome: CHR20: 18004795 -18038521
Locus: 20p11.23
Gene Diseases
The DRAM1 OVOL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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