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DRAM1-NUP107 Fusion FISH Probe

The DRAM1-NUP107 Fusion FISH Probe is used to confirm a fusion of the DRAM1 and NUP107 genes. The fusion of the DRAM1 and NUP107 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DRAM1-NUP107-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DRAM1-NUP107-20-RERE 20 (40 μL) 200 μL
DRAM1-NUP107-20-REOR 20 (40 μL) 200 μL
DRAM1-NUP107-20-REGO 20 (40 μL) 200 μL
DRAM1-NUP107-20-REGR 20 (40 μL) 200 μL
DRAM1-NUP107-20-REAQ 20 (40 μL) 200 μL
DRAM1-NUP107-20-ORRE 20 (40 μL) 200 μL
DRAM1-NUP107-20-OROR 20 (40 μL) 200 μL
DRAM1-NUP107-20-ORGO 20 (40 μL) 200 μL
DRAM1-NUP107-20-ORAQ 20 (40 μL) 200 μL
DRAM1-NUP107-20-GORE 20 (40 μL) 200 μL
DRAM1-NUP107-20-GOOR 20 (40 μL) 200 μL
DRAM1-NUP107-20-GOGO 20 (40 μL) 200 μL
DRAM1-NUP107-20-GOGR 20 (40 μL) 200 μL
DRAM1-NUP107-20-GOAQ 20 (40 μL) 200 μL
DRAM1-NUP107-20-GRRE 20 (40 μL) 200 μL
DRAM1-NUP107-20-GROR 20 (40 μL) 200 μL
DRAM1-NUP107-20-GRGO 20 (40 μL) 200 μL
DRAM1-NUP107-20-GRGR 20 (40 μL) 200 μL
DRAM1-NUP107-20-GRAQ 20 (40 μL) 200 μL
DRAM1-NUP107-20-AQRE 20 (40 μL) 200 μL
DRAM1-NUP107-20-AQOR 20 (40 μL) 200 μL
DRAM1-NUP107-20-AQGO 20 (40 μL) 200 μL
DRAM1-NUP107-20-AQGR 20 (40 μL) 200 μL
DRAM1-NUP107-20-AQAQ 20 (40 μL) 200 μL

DRAM1 Gene Summary

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]

Gene Name: DNA Damage Regulated Autophagy Modulator 1

Chromosome: CHR12: 102271104 -102317401

Locus: 12q23.2

NUP107 Gene Summary

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Gene Name: Nucleoporin 107

Chromosome: CHR12: 69080730 -69136473

Locus: 12q15

Gene Diseases

The DRAM1 NUP107 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.