DR1-CCDC18 Fusion FISH Probe
The DR1-CCDC18 Fusion FISH Probe is used to confirm a fusion of the DR1 and CCDC18 genes. The fusion of the DR1 and CCDC18 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DR1-CCDC18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-RERE | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-REOR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-REGO | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-REGR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-REAQ | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-ORRE | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-OROR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-ORGO | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-ORAQ | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GORE | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GOOR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GOGO | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GOGR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GOAQ | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GRRE | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GROR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GRGO | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GRGR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-GRAQ | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-AQRE | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-AQOR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-AQGO | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-AQGR | 20 (40 μL) | 200 μL |
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| DR1-CCDC18-20-AQAQ | 20 (40 μL) | 200 μL |
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DR1 Gene Summary
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008]
Gene Name: Down-regulator Of Transcription 1
Chromosome: CHR1: 93811477 -93828148
Locus: 1p22.1
CCDC18 Gene Summary
The Coiled-coil Domain Containing 18 (CCDC18) gene is located on chr1 :93646280-93744287 at 1p22.1.
Gene Name: Coiled-coil Domain Containing 18
Chromosome: CHR1: 93646280 -93744287
Locus: 1p22.1
Gene Diseases
The DR1 CCDC18 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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