DPYSL2-BNIP3L Fusion FISH Probe
The DPYSL2-BNIP3L Fusion FISH Probe is used to confirm a fusion of the DPYSL2 and BNIP3L genes. The fusion of the DPYSL2 and BNIP3L genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DPYSL2-BNIP3L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DPYSL2-BNIP3L-20-AQAQ | 20 (40 μL) | 200 μL |
|
BNIP3L Gene Summary
This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]
Gene Name: BCL2 Interacting Protein 3 Like
Chromosome: CHR8: 26240522 -26270644
Locus: 8p21.2
DPYSL2 Gene Summary
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Dihydropyrimidinase Like 2
Chromosome: CHR8: 26371708 -26515693
Locus: 8p21.2
Gene Diseases
The DPYSL2 BNIP3L Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|