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DPYD-CSNK1G1 Fusion FISH Probe

The DPYD-CSNK1G1 Fusion FISH Probe is used to confirm a fusion of the DPYD and CSNK1G1 genes. The fusion of the DPYD and CSNK1G1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DPYD-CSNK1G1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-RERE 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-REOR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-REGO 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-REGR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-REAQ 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-ORRE 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-OROR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-ORGO 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-ORAQ 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GORE 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GOOR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GOGO 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GOGR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GOAQ 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GRRE 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GROR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GRGO 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GRGR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-GRAQ 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-AQRE 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-AQOR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-AQGO 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-AQGR 20 (40 μL) 200 μL
DPYD-CSNK1G1-20-AQAQ 20 (40 μL) 200 μL

DPYD Gene Summary

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Gene Name: Dihydropyrimidine Dehydrogenase

Chromosome: CHR1: 97543299 -98386615

Locus: 1p21.3

CSNK1G1 Gene Summary

This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016]

Gene Name: Casein Kinase 1 Gamma 1

Chromosome: CHR15: 64457715 -64648442

Locus: 15q22.31

Gene Diseases

The DPYD CSNK1G1 Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.