DPY19L2-MRPL1 Fusion FISH Probe
The DPY19L2-MRPL1 Fusion FISH Probe is used to confirm a fusion of the DPY19L2 and MRPL1 genes. The fusion of the DPY19L2 and MRPL1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DPY19L2-MRPL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-RERE | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-REOR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-REGO | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-REGR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-REAQ | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-ORRE | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-OROR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-ORGO | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GORE | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GOOR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GOGO | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GOGR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GRRE | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GROR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GRGO | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GRGR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-AQRE | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-AQOR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-AQGO | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-AQGR | 20 (40 μL) | 200 μL |
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| DPY19L2-MRPL1-20-AQAQ | 20 (40 μL) | 200 μL |
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MRPL1 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein L1
Chromosome: CHR4: 78783804 -78873944
Locus: 4q21.1
DPY19L2 Gene Summary
The protein encoded by this gene belongs to the dpy-19 family. It is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9). [provided by RefSeq, Dec 2011]
Gene Name: Dpy-19 Like 2
Chromosome: CHR12: 63952692 -64062354
Locus: 12q14.2
Gene Diseases
The DPY19L2 MRPL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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