DPF3-TDP1 Fusion FISH Probe
The DPF3-TDP1 Fusion FISH Probe is used to confirm a fusion of the DPF3 and TDP1 genes. The fusion of the DPF3 and TDP1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DPF3-TDP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-RERE | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-REOR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-REGO | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-REGR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-REAQ | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-ORRE | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-OROR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-ORGO | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GORE | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GOOR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GOGO | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GOGR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GRRE | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GROR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GRGO | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GRGR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-AQRE | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-AQOR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-AQGO | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-AQGR | 20 (40 μL) | 200 μL |
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| DPF3-TDP1-20-AQAQ | 20 (40 μL) | 200 μL |
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DPF3 Gene Summary
This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Gene Name: Double PHD Fingers 3
Chromosome: CHR14: 73136659 -73360809
Locus: 14q24.2
TDP1 Gene Summary
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
Gene Name: Tyrosyl-DNA Phosphodiesterase 1
Chromosome: CHR14: 90422245 -90511108
Locus: 14q32.11
Gene Diseases
The DPF3 TDP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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