DPF2-PPP1R10 Fusion FISH Probe
The DPF2-PPP1R10 Fusion FISH Probe is used to confirm a fusion of the DPF2 and PPP1R10 genes. The fusion of the DPF2 and PPP1R10 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DPF2-PPP1R10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-RERE | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-REOR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-REGO | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-REGR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-REAQ | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-ORRE | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-OROR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-ORGO | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-ORAQ | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GORE | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GOOR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GOGO | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GOGR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GOAQ | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GRRE | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GROR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GRGO | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GRGR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-GRAQ | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-AQRE | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-AQOR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-AQGO | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-AQGR | 20 (40 μL) | 200 μL |
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| DPF2-PPP1R10-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP1R10 Gene Summary
This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Name: Protein Phosphatase 1 Regulatory Subunit 10
Chromosome: CHR6_mcf_hap5: 1950036 -1966876
Locus: 6p21.33
DPF2 Gene Summary
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]
Gene Name: Double PHD Fingers 2
Chromosome: CHR11: 65101224 -65120451
Locus: 11q13.1
Gene Diseases
The DPF2 PPP1R10 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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