DPF2-CDC42EP2 Fusion FISH Probe
The DPF2-CDC42EP2 Fusion FISH Probe is used to confirm a fusion of the DPF2 and CDC42EP2 genes. The fusion of the DPF2 and CDC42EP2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DPF2-CDC42EP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-RERE | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-REOR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-REGO | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-REGR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-REAQ | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-ORRE | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-OROR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-ORGO | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GORE | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GOOR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GOGO | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GOGR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GRRE | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GROR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GRGO | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GRGR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-AQRE | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-AQOR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-AQGO | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-AQGR | 20 (40 μL) | 200 μL |
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| DPF2-CDC42EP2-20-AQAQ | 20 (40 μL) | 200 μL |
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DPF2 Gene Summary
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]
Gene Name: Double PHD Fingers 2
Chromosome: CHR11: 65101224 -65120451
Locus: 11q13.1
CDC42EP2 Gene Summary
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011]
Gene Name: CDC42 Effector Protein 2
Chromosome: CHR11: 65082288 -65089900
Locus: 11q13.1
Gene Diseases
The DPF2 CDC42EP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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