DOT1L-PSG11 Fusion FISH Probe
The DOT1L-PSG11 Fusion FISH Probe is used to confirm a fusion of the DOT1L and PSG11 genes. The fusion of the DOT1L and PSG11 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOT1L-PSG11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-RERE | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-REOR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-REGO | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-REGR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-REAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-ORRE | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-OROR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-ORGO | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GORE | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GOOR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GOGO | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GOGR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GRRE | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GROR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GRGO | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GRGR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-AQRE | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-AQOR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-AQGO | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-AQGR | 20 (40 μL) | 200 μL |
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| DOT1L-PSG11-20-AQAQ | 20 (40 μL) | 200 μL |
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PSG11 Gene Summary
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
Gene Name: Pregnancy Specific Beta-1-glycoprotein 11
Chromosome: CHR19: 43511808 -43530631
Locus: 19q13.31
DOT1L Gene Summary
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]
Gene Name: DOT1 Like Histone Lysine Methyltransferase
Chromosome: CHR19: 2164147 -2232577
Locus: 19p13.3
Gene Diseases
The DOT1L PSG11 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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