DOT1L-PLEKHF1 Fusion FISH Probe
The DOT1L-PLEKHF1 Fusion FISH Probe is used to confirm a fusion of the DOT1L and PLEKHF1 genes. The fusion of the DOT1L and PLEKHF1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOT1L-PLEKHF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-RERE | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-REOR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-REGO | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-REGR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-REAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-ORRE | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-OROR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-ORGO | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GORE | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GOOR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GOGO | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GOGR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GRRE | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GROR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GRGO | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GRGR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-AQRE | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-AQOR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-AQGO | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-AQGR | 20 (40 μL) | 200 μL |
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| DOT1L-PLEKHF1-20-AQAQ | 20 (40 μL) | 200 μL |
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PLEKHF1 Gene Summary
The Pleckstrin Homology And FYVE Domain Containing 1 (PLEKHF1) gene is located on chr19 :30156326-30166383 at 19q12.
Gene Name: Pleckstrin Homology And FYVE Domain Containing 1
Chromosome: CHR19: 30156326 -30166383
Locus: 19q12
DOT1L Gene Summary
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]
Gene Name: DOT1 Like Histone Lysine Methyltransferase
Chromosome: CHR19: 2164147 -2232577
Locus: 19p13.3
Gene Diseases
The DOT1L PLEKHF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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