DOCK8-OSBP Fusion FISH Probe
The DOCK8-OSBP Fusion FISH Probe is used to confirm a fusion of the DOCK8 and OSBP genes. The fusion of the DOCK8 and OSBP genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOCK8-OSBP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-RERE | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-REOR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-REGO | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-REGR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-REAQ | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-ORRE | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-OROR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-ORGO | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GORE | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GOOR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GOGO | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GOGR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GRRE | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GROR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GRGO | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GRGR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-AQRE | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-AQOR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-AQGO | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-AQGR | 20 (40 μL) | 200 μL |
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| DOCK8-OSBP-20-AQAQ | 20 (40 μL) | 200 μL |
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OSBP Gene Summary
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase [provided by RefSeq, Jul 2008]
Gene Name: Oxysterol Binding Protein
Chromosome: CHR11: 59341870 -59383617
Locus: 11q12.1
DOCK8 Gene Summary
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
Gene Name: Dedicator Of Cytokinesis 8
Chromosome: CHR9: 214864 -465259
Locus: 9p24.3
Gene Diseases
The DOCK8 OSBP Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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