DOCK7-ADAM32 Fusion FISH Probe
The DOCK7-ADAM32 Fusion FISH Probe is used to confirm a fusion of the DOCK7 and ADAM32 genes. The fusion of the DOCK7 and ADAM32 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOCK7-ADAM32-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-RERE | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-REOR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-REGO | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-REGR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-REAQ | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-ORRE | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-OROR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-ORGO | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GORE | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GOOR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GOGO | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GOGR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GRRE | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GROR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GRGO | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GRGR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-AQRE | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-AQOR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-AQGO | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-AQGR | 20 (40 μL) | 200 μL |
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| DOCK7-ADAM32-20-AQAQ | 20 (40 μL) | 200 μL |
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DOCK7 Gene Summary
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: Dedicator Of Cytokinesis 7
Chromosome: CHR1: 62920396 -63153969
Locus: 1p31.3
ADAM32 Gene Summary
This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Gene Name: ADAM Metallopeptidase Domain 32
Chromosome: CHR8: 38965049 -39142436
Locus: 8p11.22
Gene Diseases
The DOCK7 ADAM32 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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