DOCK6-CCDC130 Fusion FISH Probe
The DOCK6-CCDC130 Fusion FISH Probe is used to confirm a fusion of the DOCK6 and CCDC130 genes. The fusion of the DOCK6 and CCDC130 genes has been associated with Acute Myeloid Leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOCK6-CCDC130-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-RERE | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-REOR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-REGO | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-REGR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-REAQ | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-ORRE | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-OROR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-ORGO | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GORE | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GOOR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GOGO | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GOGR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GRRE | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GROR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GRGO | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GRGR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-AQRE | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-AQOR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-AQGO | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-AQGR | 20 (40 μL) | 200 μL |
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| DOCK6-CCDC130-20-AQAQ | 20 (40 μL) | 200 μL |
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DOCK6 Gene Summary
This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2. [provided by RefSeq, Dec 2011]
Gene Name: Dedicator Of Cytokinesis 6
Chromosome: CHR19: 11309970 -11373157
Locus: 19p13.2
CCDC130 Gene Summary
The Coiled-coil Domain Containing 130 (CCDC130) gene is located on chr19 :13858752-13874106 at 19p13.13.
Gene Name: Coiled-coil Domain Containing 130
Chromosome: CHR19: 13858752 -13874106
Locus: 19p13.13
Gene Diseases
The DOCK6 CCDC130 Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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