DOCK1-GANC Fusion FISH Probe
The DOCK1-GANC Fusion FISH Probe is used to confirm a fusion of the DOCK1 and GANC genes. The fusion of the DOCK1 and GANC genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOCK1-GANC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-RERE | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-REOR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-REGO | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-REGR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-REAQ | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-ORRE | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-OROR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-ORGO | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GORE | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GOOR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GOGO | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GOGR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GRRE | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GROR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GRGO | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GRGR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-AQRE | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-AQOR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-AQGO | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-AQGR | 20 (40 μL) | 200 μL |
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| DOCK1-GANC-20-AQAQ | 20 (40 μL) | 200 μL |
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DOCK1 Gene Summary
This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: Dedicator Of Cytokinesis 1
Chromosome: CHR10: 128594022 -129250780
Locus: 10q26.2
GANC Gene Summary
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]
Gene Name: Glucosidase Alpha, Neutral C
Chromosome: CHR15: 42566365 -42645864
Locus: 15q15.1
Gene Diseases
The DOCK1 GANC Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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