DOCK1-DPCD Fusion FISH Probe
The DOCK1-DPCD Fusion FISH Probe is used to confirm a fusion of the DOCK1 and DPCD genes. The fusion of the DOCK1 and DPCD genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOCK1-DPCD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-RERE | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-REOR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-REGO | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-REGR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-REAQ | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-ORRE | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-OROR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-ORGO | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GORE | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GOOR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GOGO | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GOGR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GRRE | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GROR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GRGO | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GRGR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-AQRE | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-AQOR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-AQGO | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-AQGR | 20 (40 μL) | 200 μL |
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| DOCK1-DPCD-20-AQAQ | 20 (40 μL) | 200 μL |
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DOCK1 Gene Summary
This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: Dedicator Of Cytokinesis 1
Chromosome: CHR10: 128594022 -129250780
Locus: 10q26.2
DPCD Gene Summary
This gene in mouse encodes a protein that may be involved in the generation and maintenance of ciliated cells. In mouse, expression of this gene increases during ciliated cell differentiation, and disruption of this gene has been linked to primary ciliary dyskinesia. [provided by RefSeq, Jul 2016]
Gene Name: Deleted In Primary Ciliary Dyskinesia Homolog (mouse)
Chromosome: CHR10: 103348088 -103369410
Locus: 10q24.32
Gene Diseases
The DOCK1 DPCD Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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