DOCK1-APBA1 Fusion FISH Probe
The DOCK1-APBA1 Fusion FISH Probe is used to confirm a fusion of the DOCK1 and APBA1 genes. The fusion of the DOCK1 and APBA1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DOCK1-APBA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-RERE | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-REOR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-REGO | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-REGR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-REAQ | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-ORRE | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-OROR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-ORGO | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GORE | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GOOR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GOGO | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GOGR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GRRE | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GROR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GRGO | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GRGR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-AQRE | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-AQOR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-AQGO | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-AQGR | 20 (40 μL) | 200 μL |
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| DOCK1-APBA1-20-AQAQ | 20 (40 μL) | 200 μL |
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APBA1 Gene Summary
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]
Gene Name: Amyloid Beta Precursor Protein Binding Family A Member 1
Chromosome: CHR9: 72042448 -72287275
Locus: 9q21.12
DOCK1 Gene Summary
This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: Dedicator Of Cytokinesis 1
Chromosome: CHR10: 128594022 -129250780
Locus: 10q26.2
Gene Diseases
The DOCK1 APBA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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