DNMT3A-GTF3C2 Fusion FISH Probe
The DNMT3A-GTF3C2 Fusion FISH Probe is used to confirm a fusion of the DNMT3A and GTF3C2 genes. The fusion of the DNMT3A and GTF3C2 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNMT3A-GTF3C2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-RERE | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-REOR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-REGO | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-REGR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-REAQ | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-ORRE | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-OROR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-ORGO | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GORE | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GOOR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GOGO | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GOGR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GRRE | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GROR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GRGO | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GRGR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-AQRE | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-AQOR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-AQGO | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-AQGR | 20 (40 μL) | 200 μL |
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| DNMT3A-GTF3C2-20-AQAQ | 20 (40 μL) | 200 μL |
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DNMT3A Gene Summary
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
Gene Name: DNA Methyltransferase 3 Alpha
Chromosome: CHR2: 25455844 -25565459
Locus: 2p23.3
GTF3C2 Gene Summary
The General Transcription Factor IIIC Subunit 2 (GTF3C2) gene is located on chr2 :27548720-27579868 at 2p23.3.
Gene Name: General Transcription Factor IIIC Subunit 2
Chromosome: CHR2: 27548720 -27579868
Locus: 2p23.3
Gene Diseases
The DNMT3A GTF3C2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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